n gntc ngnrng, gn gn r blstc prtcl dlvry systm s dvc sd t dlvr xgns DN (trnsgns), RN, r prtn t clls. By ctng prtcls f hvy mtl wth gn f ntrst nd frng ths mcr-prjctls nt clls sng mchncl frc, n ntgrtn f dsrd gntc nfrmtn cn b ntrdcd nt dsrd clls. Th tchnq nvlvd wth sch mcr-prjctl dlvry f DN s ftn rfrrd t s blstcs, shrt fr "blgcl bllstcs".
Ths dvc s bl t trnsfrm lmst ny typ f cll nd s nt lmtd t th trnsfrmtn f th ncls; t cn ls trnsfrm rgnlls, ncldng plstds nd mtchndr.